Cissus Quadrangularis – what is it?

Cissus QuadrangularisWhat is Cissus Quadrangularis?

Cissus Quadrangularis, also called “veld grape” is a succulent plant growing in Africa, Arabia and India. The plant is known to ayuverdic medicine since ancient times and was used for a variety of ailments, especially as a restorative for broken bones.

Anabolic properties of cissus

Cissus Quadrangularis contains 3-ketosteroids, which are anabolic (help growing tissues) and anti-glucocorticoid (reduce the production of stress hormone cortisol). 3-ketosteroids are able to help heal and protect muscles, tendons, and bones through their interaction with cortisol and other hormones.

How does cortisol work?

Cortisol contributes to tissue breakdown in times of physical trauma or weakness, allowing dead proteins and other waste to exit the area. Cissus quadrangularis’ active components prevent the over-activity of these substances, and help restore tissues to their normal, healthy state. It is believed that active substances targeting the stress system also help to treat anxiety disorders.

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Cissus quadrangularis benefits

Cissus quadrangularis is used in bodybuilding and athletics to treat chronic or injury-related pain and inflammation. The use of cissus supplement can help to bring pain relief and increased performance. Tim Ferriss suggests taking cissus as a beneficial fat loss supplement for damage control during cheat days, as it aids lower blood sugar levels as well as lower serum lipids. Read more about Cissus Quadrangularis here.

Side effects of cissus

Possible side effect of extensive use of this supplement is a slight risk of gastroenteritis. A consultation with a physician can help to determine if such risk exists. A much more common side-effect of long term exposure to cissus quadrangularis is an increase in testosterone production.


The dosage of cissus quadrangularis depends on the amount of the herb contained in the supplement. You can take between one hundred and five hundred milligrams per day, the exact amount depends on the symptoms experienced as well as how long the cissus supplement is to be taken.

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